28-7 careers

We are working on cutting-edge biology, based on the breakthrough science of our world renowned scientific founders. We are looking for passionate researchers who are as excited as we are about the future of treating human disease. If you are an expert scientist in RNA and/or cancer biology, or on your way to become one, we are interested in hearing from you!

If you do not find yourself in the positions below, but are still interested in working with us, please send your cover letter and CV to Dr. Shomir Ghosh; contact@28-7tx.com

 

Scientist/Sr. Scientist in RNA biology

We seek an individual with a Ph.D. and/or post-doctoral experience working with ncRNA biogenesis and regulatory pathways for target validation, assay development, and mechanism of action studies.

Responsibilities

  • Design, conduct, and interpret studies to validate new targets in the miRNA/ncRNA space, using cell biology and biochemical methods.

  • Design, conduct, and interpret studies to determine the cellular mechanism of action of small-molecule modulators of miRNA/ncRNA biogenesis pathways.

  • Develop cell-based assays to identify/characterize for the small molecules that modulate miRNA/ncRNA biogenesis pathways.

Qualifications

  • Ph.D. in biology, biochemistry, or related field, with five years of experience in cancer biology, with an emphasis on miRNA/ncRNA regulatory and biogenesis pathways.

  • Track record of high performance in the field of miRNA/ncRNA as demonstrated by high-impact publications and presentations.

  • Extensive experience in mammalian cell culture, generation of stable clones, and development of and use of cell-based assay methods including luciferase reporter assays.

  • Adept at biochemical analysis of miRNA/ncRNA biogenesis pathways and regulatory mechanisms using gel based-systems.

  • Experience with molecular biology techniques (cloning, qPCR, etc.) and methods to interrogate gene function (CRISPR/Cas9 genome editing, siRNA transfection, over-expression systems, etc.)

  • Motivated, independent self-starter, willing to work in team environment on novel cancer therapeutics in a dynamic start-up setting.

Only Boston/Cambridge Metro Area residents will be considered for this position

 

Please send resumes and any other supporting materials to:

Dr. Shomir Ghosh
Chief Scientific Officer
Twentyeight-Seven Therapeutics
contact@28-7tx.com


Responsibilities

  • Execute routine protein-binding and enzymatic assays

  • Work with supervisor to design mechanism of action studies

  • Support protein purification with media and buffer preparation

  • Document and present research

  • Read scientific literature and contribute to group discussions

Qualifications

  • B.S./M.S. in Biochemistry or related field with at least five years of experience in
    industry or a relevant academic lab

  • Familiarity with binding assays and basic enzymology

  • Experience performing microplate-based assays

  • Proficiency in experimental design and data analysis

  • Ability to effectively communicate ideas and documented research

Only Boston/Cambridge Metro Area residents will be considered for this position

 

Please send resumes and any other supporting materials to:

Dr. Shomir Ghosh
Chief Scientific Officer
Twentyeight-Seven Therapeutics
contact@28-7tx.com

Full-Time Research Associate